生物信息与复杂疾病研究平台

生物信息与复杂疾病研究平台

研究成果

Publications

*: Co-first author
§: Co-senior author

Xuexin Yu*, Jing Hu*, Yuhao Tan, Mingyao Pan, Hongyi Zhang§, Bo Li§.
MitoTracer facilitates the identification of informative mitochondrial mutations for precise lineage reconstruction.
PLoS Computational Biology, 2025.
Xuexin Yu, Mingyao Pan, Jianfeng Ye, Cassandra A. Hathaway, Shelley S. Tworoger, Jayanthi Lea§.
Quantifiable TCR repertoire changes in prediagnostic blood specimens among patients with high-grade ovarian cancer.
Cell Reports Medicine, 2024.
Hongyi Zhang, Bo Li.
A novel computational tool for tracking cancer energy hijacking from immune cells.
Clinical and Translational Medicine, 2024.
Hongyi Zhang*, Xuexin Yu*, Jianfeng Ye*, Huiyu Li, Jing Hu, Yuhao Tan, Yan Fang, Esra Akbay, Fulong Yu, Chen Weng, Vijay G. Sankaran, Robert M. Bachoo, Elizabeth Maher, John Minna, Anli Zhang§, Bo Li§.
Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution.
Cancer Cell, 2023.
Xuexin Yu*, Wanrun Lin*, Alexandra Spirtos*, Yan Wang, Hao Chen, Jianfeng Ye, Jessica Parker, Ci Ci Liu, Yiying Wang, Gabriella Quinn, Feng Zhou, Setsuko K. Chambers, Cheryl Lewis, Jayanthi Lea§, Bo Li§, Wenxin Zheng§.
Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution.
BMC Medicine, 2022.
Xuexin Yu, Bo Li.
Seed or soil: Tracing the immune subsets in metastatic tumors.
Cancer Cell, 2022.
Hongyi Zhang, Xiaowei Zhan, Bo Li.
GIANA allows computationally-efficient TCR clustering and multi-disease repertoire classification by isometric transformation.
Nature Communications, 2021.
Hongyi Zhang*, Longchao Liu*, Jian Zhang, Jiahui Chen, Jianfeng Ye, Sachet Shukla, Jian Qiao, Xiaowei Zhan, Hao Chen, Catherine J Wu, Yang-Xin Fu§, Bo Li§.
Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers.
Clinical Cancer Research, 2020.
Hongyi Zhang*, Jianlong Liao*, Xinxin Zhang*, Erjie Zhao*, Xin Liang, Shangyi Luo, Jian Shi, Fulong Yu, Jinyuan Xu, Weitao Shen, Yixue Li, Yun Xiao§, and Xia Li§.
Sex difference of mutation clonality in diffuse glioma evolution .
Neuro-oncology, 2019.
Hongyi Zhang*, Shangyi Luo*, Xinxin Zhang*, Jianlong Liao*, Fei Quan, Erjie Zhao, Chenfen Zhou, Fulong Yu, Wenkang Yin, Yunpeng Zhang§, Yun Xiao§, and Xia Li§.
SEECancer: A resource for Somatic Events in Evolution of Cancer genome.
Nucleic Acids Research, 2018.
Hongyi Zhang*, Yulan Deng*, Yong Zhang*, Yanyan Ping, Hongying Zhao, Lin Pang, Xinxin Zhang, Li Wang, Chaohan Xu, Yunpeng Zhang§, Yun Xiao§, and Xia Li§.
Cooperative genomic alteration network reveals molecular classification across 12 major cancer types.
Nucleic Acids Research, 2017.